Type of Document Master's Thesis Author Kuntz, Charles A. URN etd-06082009-171014 Title Controlled cross circulation: effects on donor hemodynamics Degree Master of Science Department Veterinary Medical Sciences Advisory Committee
Advisor Name Title Johnston, Spencer A. Committee Chair Jacobson, John Committee Member Larson, Martha Moon Committee Member Lee, John C. Committee Member Martin, Robert A. Committee Member Shires, Peter K. Committee Member Keywords
Date of Defense 1994-05-12 Availability restricted Abstract
Controlled cross circulation was performed in six pairs of dogs to assess hemodynamic changes in the donor dog. Cardiopulmonary bypass was performed for 45 minutes, with an aortic cross clamp time of 3 5 minutes. Anesthesia was maintained in the donor dog with 1.8% end-tidal isoflurane. Parameters before and after controlled cross circulation were compared using a Wilcoxon Signed Rank Test.
Donor left ventricular dP/dt max, pulmonary capillary wedge pressure, blood volume, systemic vascular resistance, heart rate, total protein, platelet count, and white blood cell count did not change significantly. Donor cardiac output, end diastolic volume, central venous pressure, stroke volume, mean arterial blood pressure, and packed cell volume all decreased significantly (p
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