Title page for ETD etd-09082012-040648

Type of Document Master's Thesis
Author Cadorette, Veronica R.
URN etd-09082012-040648
Title Chemical investigation of Dicranum fulvum for anticancer activity
Degree Master of Science
Department Chemistry
Advisory Committee
Advisor Name Title
Kingston, David G. I. Committee Chair
Bell, Harold M. Committee Member
Taylor, Larry T. Committee Member
  • Bryophytes
Date of Defense 1989-08-15
Availability restricted

Biological screening of extracts of various bryophytes showed that the species Dicranum fulvum gave extracts with activity in both in vitro and in vivo bioassays. This plant was thus selected for extraction and fractionation, monitored by iin vitro bioassays.

Isolation was guided by a combination of bioassay and chemical methods, and led to the isolation of three compounds, betulin, 9,l9- cyclolanost—23—ene—3,25—diol, and B-sitosterol. Purification was achieved by open column, flash column, gel filtration, thin layer chromatography, the chromatotron and crystallization.

The isolated compounds were identified by comparisons of spectroscopic data with those of authentic samples and the matching of experimental and literature melting points and optical rotations.

  Filename       Size       Approximate Download Time (Hours:Minutes:Seconds) 
 28.8 Modem   56K Modem   ISDN (64 Kb)   ISDN (128 Kb)   Higher-speed Access 
[VT] LD5655.V855_1989.C346.pdf 2.48 Mb 00:11:27 00:05:53 00:05:09 00:02:34 00:00:13
[BTD] next to an author's name indicates that all files or directories associated with their ETD are accessible from the Virginia Tech campus network only.

Browse All Available ETDs by ( Author | Department )

dla home
etds imagebase journals news ereserve special collections
virgnia tech home contact dla university libraries

If you have questions or technical problems, please Contact DLA.