Title page for ETD etd-11292012-040229

Type of Document Dissertation
Author Rifkin, Robert Joel
URN etd-11292012-040229
Title The effect of acetoacetate, organosulfur compounds and hormones on the activity of the liver mitochondria
Degree PhD
Department Biochemistry and Nutrition
Advisory Committee
Advisor Name Title
Engel, R. W. Committee Chair
Huber, J. T. Committee Member
Miller, R. F. Committee Member
  • Cattle
Date of Defense 1963-06-05
Availability restricted

The mitochondrial utilization of a-ketoglutaric and pyruvic acids have been found to be depressed in guinea pig and bovine ketosis. Addition of sodium acetoacetate to the reaction medium resulted in depressed oxidation of pyruvate and 1-ketoglutarate of isolated normal rat liver mitochondria.

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