Type of Document Master's Thesis Author Schroeder, Matthew O URN etd-12302008-063639 Title Biotribology :articular cartilage friction, wear, and lubrication Degree Master of Science Department Mechanical Engineering Advisory Committee
Advisor Name Title Furey, Michael J. Committee Chair Eiss, Norman S. Jr. Committee Member Veit, Hugo P. Committee Member Keywords
- joint disease
Date of Defense 1995-07-05 Availability restricted AbstractThis study developed, explored, and refined techniques for the in vitro study of cartilage-on-cartilage friction, deformation, and wear. Preliminary results of in vitro cartilage-on- cartilage experiments with emphasis on wear and
biochemistry are presented. Cartilage-bone specimens were obtained from the stifle joints of steers from a separate controlled study. The load, sliding speed, and traverse of the lower specimens were held constant as lubricant and test length were varied. Lubricants tested consisted of a phosphate buffered saline solution, bovine serum, and bovine synovial fluid.
Synovial fluid as a lubricant produced the least amount of damage to the cartilage. Serum produced more wear and damage than synovial fluid, but less
than buffered saline (which produced the most damage). Three-hour tests produced more wear than one-hour tests, with severe damage to the lower plug
in several of the three-hour tests.
Analysis of the results was possible through: data acquisition of normal load, tangential load, and LVDT displacement; photomacrographs; ESEM and
SEM surface studies; stained cross-sectional slides of cartilage; and hydroxyproline analysis of cartilage wear.
Detailed procedures and discussion of results are presented along with recommended changes for future biotribology research.
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