Title page for ETD etd-11182008-063632
|Type of Document
||Amanna, Karen Ruggio
||Folate status and milk folate concentration in lactating women
||Master of Science
||Human Nutrition, Foods, and Exercise
|Thomas, Elizabeth A.
|Schlenker, Eleanor D.
|Date of Defense
Lactating women have an increased requirement for folate which contributes
to their risk for suboptimal folate status. Although milk folate secretion
appears to be maintained independent of folate intake and maternal folate
status, studies with animal species have demonstrated a relationship between
iron deficiency and impaired milk folate secretion. Objectives of this study
were to monitor the folate status of lactating women and to examine the
relationship among folate intake, dietary iron, folate status, iron status and
milk folate. Seven-day dietary records, milk samples, and blood samples were
collected monthly for four months from five lactating women. Dietary iron
and folate was analyzed. Milk folate, serum ferritin, serum folate, and red
blood cell (rbc) folate concentrations were measured. Mean folate and iron
intakes were 495 ± l05μg/d and 24 ± 4 mg/d, respectively. All women had normal rbc folate and serum ferritin values during the study. Milk folate
increased (p=.06) from 35± 10 μg/L in month one to 69 ± 30 μg/L in month
three. Dietary and rbc folate were not significantly correlated with milk folate.
There was a significant positive correlation between milk folate and serum
folate (r = .48, p= .04) and between milk folate and iron intake (r=.63, p=.003).
Results indicate that the folate intake in this population of lactating women
was sufficient to maintain adequate folate stores. Results also suggest a
relationship between iron intake and milk folate. Research is needed to
determine dietary requirements during lactation and to investigate the
relationship between dietary iron and milk folate.
|| Approximate Download Time
| 28.8 Modem
|| 56K Modem
|| ISDN (64 Kb)
|| ISDN (128 Kb)
|| Higher-speed Access
next to an author's name indicates that all
files or directories associated with their ETD
are accessible from the Virginia Tech campus network only.
If you have questions or technical
problems, please Contact DLA.